Autism is a developmental disorder characterized by severe abnormalities in communication, social awareness and skills, and behavior. Before the 1980s, autism occurred in 2 to 5 of every 10,000 children. Today about 1 in every 110 children gets autism. This rapid increase cannot only be attributed to improved diagnosis, and also indicates there is more to the disorder than simply genetics. Indeed, autism is a combination of genetic predisposition with environmental factors that triggers its development.

One aspect of contributing factors, at least in a subset of children, involves gut dysfunction. Many reports describe gastrointestinal symptoms and abnormalities in up to 84% of children with autism.[1] From constipation, diarrhea, abdominal discomfort, food sensitivities and abnormal gut flora to immune dysfunction and gut and systemic inflammation, the digestive system plays a central role in many cases of autism.

One gut abnormality—lactose intolerance—found in people with autism was recently reported in the journal Autism. Intestinal disaccharidase activity was measured in 199 individuals with autism. Disaccharidase is an enzyme that breaks larger sugars (disaccharides) like lactose, maltose and sucrose into smaller sugars like glucose. Deficiency of lactase enzyme, the enzyme that breaks milk sugar, or lactose, into galactose and fructose, was found in 58 percent of autistic children and 65 percent of autistic adults. In children, boys under 5-years-old had 1.7-fold lower lactase activity than girls of the same age, indicating the problem may be more severe in boys. The study concluded that lactase deficiency is common in autistic children and may contribute to abdominal discomfort, pain and the observed abnormal behavior seen in autism. Further, the study points out that most autistic children with lactose intolerance are not identified when doctors take a clinical history.

A decrease in activity of a variety of carbohydrate-digesting enzymes has been reported in children with autism.[2] Carbohydrase and disaccharidase enzyme deficiency results in the incomplete breakdown of carbohydrates in the small intestine. These partially undigested carbs move into the colon where they are greeted by a large supply of “hungry” bacteria—including potentially pathogenic bacteria. This may explain the increased presence of Candida and Clostridia species found in the guts of autistics.[3][4]

Carbohydrate-digesting enzymes are not the only digestive enzymes that may cause problems in autism. Fat malabsorption is seen in some autistic children, resulting in fatty, loose, floating, foul-smelling stools, also known as steatorrhea. Further, a particular enzyme known as dipeptidyl peptidase-4 (DPP4) may be deficient in those with autism. This enzyme breaks a specific peptide bond in gluten and casein proteins. In fact, it is thought that a deficiency in this enzyme is responsible for the incomplete breakdown of casein and gluten peptides (known as gluteomorphins and casomorphins) that act as opioids in the central nervous system and are thought to contribute to autistic symptoms. Following a gluten-free and casein-free diet has been found helpful in many autistics because it eliminates exposure to these peptides, often relieving symptoms. Supplemental DPP4 can be given in cases where accidental ingestion of gluten- or casein-containing foods is suspected, but it is not recommended as a replacement for the gluten-free, casein-free diet.

In all, we see a variety of enzyme deficiencies in autism and it would be wise to supplement with a digestive enzyme formula that includes a variety of enzymes. Further, due to the many digestive abnormalities seen in autism, the HOPE Formula (High-fiber, Omega oils, Probiotics and digestive Enzymes) is a wise daily maintenance program to support gut health.

[2] Horvath K, et al., “Gastrointestinal abnormalities in children with autistic disorder.” J Pediatr 1999;135:559-63.

[3] Finegold SM, et al., “Gastrointestinal microflora studies in late-onset autism.” Clin Infect Dis. 2002 Sep 1;35(Suppl 1):S6-S16.

[4] Shaw W, et al., “Assessment of antifungal drug therapy in autism by measurement of suspected microbial metabolites in urine with gas chromatography—mass spectrometry. The Clinical Practice of Alternative Medicine Magazine. 2000;1:15-26.

Leonard Smith, M.D.

Dr. Leonard Smith is a prominent Board-Certified, general, gastrointestinal and vascular surgeon who had a successful private practice for 25 years. In addition to his active surgery practice, he also incorporated lifestyle, diet, supplementation, exercise, detoxification, and stress management into many of the therapies he would prescribe. Many of his patients with cancer, cardiovascular disease, and other serious illnesses did so well under his treatment regimes that he began to devote most of his career to foundational health care and preventive medicine.

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“Renew You” Challenge – This weekly challenge is about how heart health begins in your mouth.
Your digestive tract (what I like to call the gut) begins in your mouth. The thought, smell or sight of food triggers the release of amylase enzymes in the mouth to begin the digestion of carbohydrates. The chewing process is also important for the physical breakdown of foods and mixing them with amylase enzyme in saliva.

But guess what, there is much more to the mouth than saliva and teeth. There is a bacterial balance that can contribute to the health of the rest of the body, in a somewhat similar way as it exists in the intestine.

This is a relatively new concept and one that I find interesting. Certain pathogenic bacteria haven been known to cause the buildup of plaque and the development of gum disease. This is not new news. But what is new, is that these bacteria (and thus, gum disease) are linked to the development of heart disease.

A recent study has found that these bacteria are actually able to get into the bloodstream directly from the mouth. (Have you heard of leaky gut syndrome? This could be called leaky gum syndrome). These renegade bacteria trigger the development of blood clots, which lead to heart disease.

We can no longer look at different parts of the body and see them as separate. Everything is interconnected, and what happens in one area of the body has an effect on another. This is especially true in the digestive tract, due to its function, location, and direct connections to so many parts of the body.

So brush off that dental floss if it’s looking a little dusty. Everyday flossing, cutting back on sugar and refined carbohydrates, and brushing at least twice a day are great ways to keep your heart (and your body) healthy.

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“Renew You” Challenge – Be a part of my Weekly Challenge to help set you off in the right direction for bringing health to your week. So this week I wanted to challenge the way you eat. 

Heartburn, indigestion, gas and bloating. At one time or another you’ve probably experienced a bout of post-meal discomfort that had you thinking, “What on earth did I eat that just isn’t sitting right??” Well, guess what? You were on the right track.

Most of the time things like heartburn and upset stomach can be prevented just by being choosy about what we put on our plate, since a lot of foods have natural components that can help our digestive system do its job. That’s right—Mother Nature knew what she was doing, folks!

Yogurt and cottage cheese, for example, contain probiotics that help keep your digestive system in balance and promote regularity, and so do fermented foods like kefir, sauerkraut, miso and tempeh.

Raw fruits and veggies contain powerful enzymes that work to break down all kinds of foods like carbohydrates, fats, sugars, and dairy foods, and they also help your body absorb nutrients. Papaya and pineapple, for example, contain an enzyme called papain that is especially helpful for digesting protein in the diet.

And—no surprise here—fiber is also important for healthy digestion. A good blend of soluble and insoluble fiber from fruits, vegetables, whole grains, legumes and nuts helps keep food moving through your intestines and promotes regular, healthy bowel movements.

So this week I want you to really pay attention to your meals and try to choose foods that benefit your digestive system rather than those that work against it. Steer clear of high-fat, sugary and processed foods, and load up on easy-to-stomach foods like fresh produce, whole grains, and probiotic-rich yogurt and fermented foods—your belly will thank you!

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Lactose intolerance. It’s one of those phrases we hear a lot, but the truth is, a lot of folks don’t really know what it means. Case in point? I was reading an article in the newspaper the other day in which the author concluded that most Americans misunderstand lactose intolerance…but my own conclusion was that the author herself misunderstood the condition!

In the article she stated that many people avoid dairy products “because they mistakenly think they’re lactose intolerant”. But really, that’s only half the story. Lactose intolerance involves an inability to digest lactose, which is the sugar found in dairy products, but the reason so many people avoid dairy has more to do with an allergy or sensitivity to casein—a protein found in milk—and not because of lactose intolerance.

And yes, while the author expressed a valid concern about people avoiding dairy when they may not even be lactose intolerant, she failed to talk about the possibility of looking into milk protein sensitivity (similar to gluten sensitivity) in order to address the problem…and the differences between the two are pretty significant if you’re used to avoiding an entire food group!

Essentially, people who are allergic to or sensitive to casein usually need to avoid all dairy products, but those who are lactose intolerant can sometimes eat dairy in small portions, or with the help of natural lactase enzymes. Imagine thinking you couldn’t eat dairy at all and then finding out that you still may be able to enjoy some of your favorite foods—I’m sure it would be welcome news to a lot of people. So hopefully this clears up a little of the confusion folks have about lactose intolerance, and maybe it’s even helped you see things differently in your own diet!

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Got heartburn? GERD? Listen up! This isn’t new news, but it’s news I think everyone should know: Using proton pump inhibitors (commonly known as PPIs) for extended periods of time could make you more likely to suffer osteoporosis-related bone fractures.

Why do I think this is so important? Because folks, PPIs are the third-highest-selling class of drugs on the market today, and one of the most popular PPIs—Nexium® (you know, the little purple pill)—has the second-highest retail sales among all drugs sold in the U.S. That means there’s a good chance that you or someone you know is taking one. So let’s review:

What is a PPI? A PPI is a drug that blocks the production of the enzyme in the stomach that produces acid. PPIs are commonly prescribed for the following conditions:

• Ulcers
• Gastroesophageal reflux disease (GERD, or acid reflux)
• Zollinger-Ellison syndrome (a rare disease that results in the overproduction of gastrin, which releases excess stomach acid)

Do PPIs work? Yes, on the surface they work remarkably well. They reduce stomach acid, which reduces pain almost instantly, but—and I can’t stress this enough—covering up the symptoms does not solve the underlying problem. And even though it’s recommended that PPIs aren’t used for more than 8 to 12 weeks at a time, a lot of people are taking them for much longer, probably because they’re so readily available!

What worries me is that people just don’t know enough about the side effects and complications of using PPIs longer than they should, but there are so many—which brings me back to my point. Research shows that long-term PPI use is linked to an increased risk of osteoporosis-related bone fractures, especially hip, wrist and spine fractures.   

What’s the connection? Simple: Hypochlorhydria (which is just a fancy term for low stomach acid) can decrease calcium absorption, and PPIs create hypochlorhydria in the stomach. This results in reduced calcium absorption, and if the body doesn’t get enough calcium from the diet, where does it take it from? Your bones!

It’s a vicious cycle, but it’s one that can be avoided by taking steps to establish a strong foundation of digestive health. These include eating a high-fiber diet and avoiding heavily processed, high-sugar and high-fat foods, as well as taking daily enzymes, probiotics and beneficial Omega-3 oils. I’ll cover more on the dangers of PPI use in future blogs, so stay tuned. But remember—there are safe and effective natural alternatives to using PPIs, and all it takes is a quick trip to the health food store!

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Are there days when you feel sluggish and tired, and you just don’t have the energy to do the things you enjoy? Do digestive problems like constipation, diarrhea or even gas and bloating seem to weigh you down? Or do you sometimes feel more scatterbrained and forgetful than usual and wish there was a way to feel like yourself again? It’s time to discover the natural solution that will bring back the vibrant health and energy you deserve.

Tomorrow on the Poop Scoop I’ll share with you the secret to better digestion and a clearer mind and body, and it all begins with High fiber, Omega oils, Probiotics and Enzymes. These four nutritional supplements are the key to my H.O.P.E. Formula, and they have helped millions of people just like you live healthier every day. But where should you start? And how much do you need every day to get the most benefit? Join me and learn everything you need to know!

Log on and listen to Brenda’s Poop Scoop LIVE every Wednesday from 4-5 pm (EST) right from your computer. Missed an episode? Visit the Episode Directory on my website and listen to past shows from the archive.

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It’s a subject you’ve heard me talk about before, but considering new research it’s definitely worth repeating. A recent CBS news segment revealed that not one but five new studies showed that using acid-blocking drugs called proton pump inhibitors (PPIs) can be potentially dangerous to your health, and that “more than half of prescriptions for these drugs are unnecessary”. Folks, this is an eye-opener if there ever was one!

Every year more than 100 million Americans are prescribed PPIs to help relieve symptoms of heartburn and acid reflux, but what many people don’t know is that these drugs often come with some pretty serious side effects—including a nearly 75 percent greater risk of developing a severe intestinal infection known as C. diff, according to new evidence. Essentially, taking PPIs upsets the healthy bacterial balance in your intestines (which is where the majority of your natural immune defenses can be found), leaving your body vulnerable to illness and infection.

Widespread PPI use has also been linked to higher rates of pneumonia, as well as esophageal candidiasis (yeast overgrowth), inflammation of the stomach lining, increased permeability of upper GI tract lining, and even osteoporosis-related bone fractures due to the fact that PPIs block calcium absorption in the body. Because long-term PPI use also leads to hypochlorhydria (low stomach acid secretion), bacterial overgrowth and acetaldehyde production, PPI users have an increased risk of developing gastric cancer. 

The good news? There are simple things we can do every day to help prevent heartburn and acid reflux without relying on harmful drugs. Diet changes like limiting our intake of caffeine, alcohol, chocolate and fatty or spicy foods can make a big difference, along with maintaining a healthy body weight, getting plenty of exercise and quitting smoking—all pretty good advice if you ask me! Natural supplements made with ingredients such as ellagic acid (from raspberries and pomegranates) can also provide soothing relief for occasional heartburn, and digestive enzymes with added HCl can help ensure complete digestion and reduce the chances of heartburn and acid reflux happening in the first place.

The bottom line is this: why take a potentially dangerous drug when smarter, safer alternatives exist? My hope is that the more people learn about PPIs and their side effects—including why they may not even need them in the first place—the more people will take steps to improve their digestive health naturally.

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Renew You Challenge

Be a part of my Weekly Challenge (I mean, opportunity!) to help set you off on the right foot and in the right direction for bringing better health to your week. Add it to your calendar and  join us every Monday! 

Pay Attention to Your Food!  Be honest – how many times have you found yourself standing at the kitchen counter or over the sink just popping stuff in your mouth without even thinking about it? Or do you do things like read the newspaper, surf the net or watch TV during meals? I’ll give you a second to wipe that guilty look off your face…

The truth is, most of the time we’re so distracted that we never even take the time to chew our food let alone taste it, and I’m sure I don’t have to tell you how bad that is! So this week’s challenge is all about getting rid of those pesky distractions when you’re about to eat.

It’s called mindful eating, and I want you to eat at least one meal every day without distractions – just you and your food. That means sitting down, and yes, chewing your food thoroughly so those helpful enzymes in your saliva have time to start the digestive process.(And don’t even get me started about how important healthy digestion is!)

Also when you’re eating, try to really taste your food. Think about how it breaks down in your digestive tract and gives nourishment to your body. You’ve probably heard this before, but it’s worth repeating – you really are what you eat!

Let Me Know How it’s Going!  What opportunities has this challenge opened up for you? Was it easy? Any revelations?  Did you enjoy your food more?

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If you are in the United States and you eat anything at all purchased from a supermarket you are most likely aware of current food scares.  These scares involve food contaminated with harmful bacteria such as E.coli and salmonella.  We have had many in the past year involving foods such as ground beef, jalapeno peppers, tomatoes, peanuts, pistachios and white pepper.

These are frightening events seeing as in 2008 an estimated 325,000 Americans were hospitalized and more than 5,000 people died from tainted food.  Unfortunately the Food and Drug Administration currently has the resources to only inspect less than one percent of the food imported into the United States.  No wonder consumer confidence is falling. There is hope on the horizon for food safety.  A bill is currently in the House of Representatives that will give the FDA more power and funding to implement better safety standards, establish a better inspection program, and allow easier tracking of tainted food products.

In the meantime one of the best ways to protect yourself and your family from pathogenic bacteria on food is to take a daily probiotic supplement.  Probiotics, or your good bacteria, found in the digestive tract have the ability to produce substances that kill bad bacteria eaten on food.  These probiotics also crowd out the digestive tract and consume all the food source that bad bacteria would need in order to survive – ReNew Life’s Ultimate Flora Adult Formula Probiotic Supplement can help.

Another means of protection against food-bourne illness is a digestive enzyme formula containing hydrochloric acid, like Renew Life’s ParaZyme.  This acid is what is normally found in a healthy stomach when we eat.  Unfortunately lots of people, as they age and for other reasons, are lacking in this very important substance.  One of the most notable functions of our stomach acid is the natural sterilization for our food.  Without proper stomach acid you are more susceptible to bacteria and parasitic infections.

So protect your family and always have a probiotic and enzyme formula available.

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Brenda Watson, E.coli, Enzymes, FDA, hydrochloric acid, Parazyme, Probiotics, salmonella

During these tough economic times every penny counts. That is why I am doing a new series on “Staying Healthy in an Unhealthy Economy.” With so many losing their jobs and health care, how can you stay healthy? In this video, part 1 of the series, I discuss easy natural choices to invest in your health and well being.

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