Digestive Care Expert Brenda Watson

TAG | calcium

Medicated Hearts

The recommended prescription medication for high cholesterol is usually statin drugs. These drugs are widely prescribed for people with high total cholesterol, and particularly those with high LDL (bad) cholesterol levels. Recently, it was recommended that people with high levels of the inflammation marker C-reactive protein (hsCRP) in their blood should also be taking statins. High CRP indicates systemic inflammation, another risk factor for heart disease. However, people with high CRP can have normal, and even low, amounts of cholesterol.

 To further extend the reach of statin drugs, even obese children are now prescribed statins if their cholesterol levels are high. This has met with some controversy, as there have been no long-term studies on the health effects of long-term statin treatment in children.

 A recent study is trying to reign in the statin prescription epidemic by suggesting that statin drugs are overprescribed. The Johns Hopkins study, presented at the American Heart Association’s annual Scientific Sessions, found that almost 95 percent of heart attacks, strokes, or heart-related deaths occurred in people who had a measurable amount of calcium buildup in the arteries.

 The researchers found that patients on statin drugs who had no calcium buildup in their arteries only suffered five percent of heart-disease-related events. This means that the drugs may not be offering any protection in these people, yet as many as five percent of all people on statins experience severe side effects, which includes diabetes in some people.

The researchers recommend that only those patients at greatest risk, especially those with high coronary calcium scores, be given statins. Luckily, diet and lifestyle factors like exercise and stress reduction help to lower some of the risk factors for heart disease. Talk with your doctor about your options.

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PPIs and Osteoporosis

 

Got heartburn? GERD? Listen up! This isn’t new news, but it’s news I think everyone should know: Using proton pump inhibitors (commonly known as PPIs) for extended periods of time could make you more likely to suffer osteoporosis-related bone fractures.

Why do I think this is so important? Because folks, PPIs are the third-highest-selling class of drugs on the market today, and one of the most popular PPIs—Nexium® (you know, the little purple pill)—has the second-highest retail sales among all drugs sold in the U.S. That means there’s a good chance that you or someone you know is taking one. So let’s review:

What is a PPI? A PPI is a drug that blocks the production of the enzyme in the stomach that produces acid. PPIs are commonly prescribed for the following conditions:

  • Ulcers
  • Gastroesophageal reflux disease (GERD, or acid reflux)
  • Zollinger-Ellison syndrome (a rare disease that results in the overproduction of gastrin, which releases excess stomach acid)

Do PPIs work? Yes, on the surface they work remarkably well. They reduce stomach acid, which reduces pain almost instantly, but—and I can’t stress this enough—covering up the symptoms does not solve the underlying problem. And even though it’s recommended that PPIs aren’t used for more than 8 to 12 weeks at a time, a lot of people are taking them for much longer, probably because they’re so readily available!

What worries me is that people just don’t know enough about the side effects and complications of using PPIs longer than they should, but there are so many—which brings me back to my point. Research shows that long-term PPI use is linked to an increased risk of osteoporosis-related bone fractures, especially hip, wrist and spine fractures.   

What’s the connection? Simple: Hypochlorhydria (which is just a fancy term for low stomach acid) can decrease calcium absorption, and PPIs create hypochlorhydria in the stomach. This results in reduced calcium absorption, and if the body doesn’t get enough calcium from the diet, where does it take it from? Your bones!

It’s a vicious cycle, but it’s one that can be avoided by taking steps to establish a strong foundation of digestive health. These include eating a high-fiber diet and avoiding heavily processed, high-sugar and high-fat foods, as well as taking daily enzymes, probiotics and beneficial Omega-3 oils. I’ll cover more on the dangers of PPI use in future blogs, so stay tuned. But remember—there are safe and effective natural alternatives to using PPIs, and all it takes is a quick trip to the health food store!

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It’s a subject you’ve heard me talk about before, but considering new research it’s definitely worth repeating. A recent CBS news segment revealed that not one but five new studies showed that using acid-blocking drugs called proton pump inhibitors (PPIs) can be potentially dangerous to your health, and that “more than half of prescriptions for these drugs are unnecessary”. Folks, this is an eye-opener if there ever was one!

Every year more than 100 million Americans are prescribed PPIs to help relieve symptoms of heartburn and acid reflux, but what many people don’t know is that these drugs often come with some pretty serious side effects—including a nearly 75 percent greater risk of developing a severe intestinal infection known as C. diff, according to new evidence. Essentially, taking PPIs upsets the healthy bacterial balance in your intestines (which is where the majority of your natural immune defenses can be found), leaving your body vulnerable to illness and infection.

Widespread PPI use has also been linked to higher rates of pneumonia, as well as esophageal candidiasis (yeast overgrowth), inflammation of the stomach lining, increased permeability of upper GI tract lining, and even osteoporosis-related bone fractures due to the fact that PPIs block calcium absorption in the body. Because long-term PPI use also leads to hypochlorhydria (low stomach acid secretion), bacterial overgrowth and acetaldehyde production, PPI users have an increased risk of developing gastric cancer. 

The good news? There are simple things we can do every day to help prevent heartburn and acid reflux without relying on harmful drugs. Diet changes like limiting our intake of caffeine, alcohol, chocolate and fatty or spicy foods can make a big difference, along with maintaining a healthy body weight, getting plenty of exercise and quitting smoking—all pretty good advice if you ask me! Natural supplements made with ingredients such as ellagic acid (from raspberries and pomegranates) can also provide soothing relief for occasional heartburn, and digestive enzymes with added HCl can help ensure complete digestion and reduce the chances of heartburn and acid reflux happening in the first place.

The bottom line is this: why take a potentially dangerous drug when smarter, safer alternatives exist? My hope is that the more people learn about PPIs and their side effects—including why they may not even need them in the first place—the more people will take steps to improve their digestive health naturally.

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