A recent study to be published in the journal Pediatrics found that the prevalence of food allergy in children is higher than previously thought.¹ It turns out that 8 percent of children—that’s about 1 in every 13 children—are affected by food allergy. Food allergies and sensitivities are far-reaching problems contributing to many autoimmune conditions like type 1 diabetes, arthritis and psoriasis, and to neuro-inflammatory conditions like autism and attention-deficit/hyperactivity disorder (ADHD).^2-5

Food allergies and sensitivities are essentially the result of a breakdown in gut mucosal immune regulation in response to food antigens that pass through the gut. The gut-associated lymphoid tissue (GALT) makes up about 80 percent of the body’s immune system, and it resides in and around the gut. The job of the immune system in the gut is to respond to foreign invaders, like pathogens, by destroying them. At the same time, it must also not respond to the large amount of food that passes through the gut every day—this is known as oral tolerance.

When it comes to food allergies and sensitivities, building and maintaining a healthy gut lining is key. The HOPE Formula can help you to achieve this with High fiber, Omega oils, Probiotics and digestive Enzymes.   

If you have the right bacterial balance, as can be achieved with probiotics, the gut lining will be minimally inflamed and therefore minimal leakage of microbial toxins will be available to activate the GALT. The beneficial bacteria also create more of an immune tolerance with the epithelial cells that line the intestine—especially the mucosal-associated lymphocytes that are part of the epithelial lining.⁶

The right balance of soluble fiber and insoluble fiber can also minimize allergies—the soluble fiber by producing beneficial short chain fatty acids, especially butyrate, which is the primary fuel of the colonocytes; and insoluble fiber by diluting out any toxins associated with allergens that are exposed to the intestinal lining. In addition, it holds water and bulks the stools to promote better and quicker elimination, thus reducing the time of exposure to allergens.

The essential omega-3 and omega-6 oils in the right ratio promote immune balance in the gut lining and gut-associated immune system. Most people consume too many omega-6 oils and too few anti-inflammatory omega-3 oils. Omega-3 supplements can help reverse this imbalance. Digestive enzymes help by effectively breaking down proteins, fats, and carbs into less-antigenic food particles so that the intestinal (epithelial) lining does not react in an allergic, immunologic manner.  

HOPE should be a foundational health concept to help eliminate and/or prevent food allergies, especially when combined with avoidance of known allergenic foods and a rotation diet that avoids repetition of any given sensitive food for at least 3 to 4 days before eating it again. 

1. Gupta RS, et al., “The prevalence, severity, and distribution of childhood food allergy in the United States.” Pediatrics. 2011 Jun 20. [Epub ahead of print]
2. Wasmuth HE and Kolb H, “Cow’s milk and immune-mediated diabetes.” Proc Nutr Soc. 2000 Nov;59(4):573-9.
3. Hvatum M, et al., “The gut-joint axis: cross reactive food antibodies in rheumatoid arthritis.” Gut. 2006 Sep;55(9):1240-7.
4. Abenavoli M, et al., “Celiac disease and skin: psoriasis association.” World J Gastroenterol. 2007 Apr 14;13(14):2138-9.
5. Curtis LT and Patel K, “Nutritional and environmental approaches to preventing and treating autism and attention deficit hyperactivity disorder (ADHD): a review.” J Altern Complement Med. 2008 Jan-Feb;14(1):79-85.
6. Savilahti E, et al., “Pre and probiotics in the prevention and treatment of food allergy.” Curr Opin Allergy Clin Immunol. 2008 Jun;8(3):243-8.

Leonard Smith, M.D.

Dr. Leonard Smith is a prominent Board-Certified, general, gastrointestinal and vascular surgeon who had a successful private practice for 25 years. In addition to his active surgery practice, he also incorporated lifestyle, diet, supplementation, exercise, detoxification, and stress management into many of the therapies he would prescribe. Many of his patients with cancer, cardiovascular disease, and other serious illnesses did so well under his treatment regimes that he began to devote most of his career to foundational health care and preventive medicine.

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Celiac disease is an autoimmune disease involving a reaction in the gut to gliadin, the gluten protein found in wheat, barley and rye. This gut reaction destroys the body’s own intestinal lining cells, a process known as autoimmunity. The treatment of celiac disease is complete avoidance of gluten and gluten-containing foods. If not treated properly, the autoimmunity can manifest in other areas of the body, like the joints or the thyroid gland.

A recent study set out to determine at what age people develop celiac disease. Every 15 years since 1974 the number of people with celiac disease has doubled. As it turns out, the incidence of celiac disease in the elderly is almost two and a half times higher than the general population. This counters the previous perception that celiac disease usually develops during childhood.

So what factors may be leading to this late-life loss of tolerance to gluten?

Studies will need to be done to determine the exact environmental triggers, but I suspect that these people may have been living for years with either silent celiac disease (yes, celiac can exist in the gut with no symptoms at all) or the milder form of gluten sensitivity.

So many people improve their health status when they eliminate gluten. Why wait until you’re elderly to find out what it might do? Try a gluten-free diet if you think that you might be sensitive.

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Celiac disease involves an autoimmune gut reaction to gluten proteins found in wheat, barley and rye. This reaction destroys the intestinal villi. Villi are the finger-like projections that line the small intestine, increasing the surface area of the intestine so that absorption of nutrients can be maximized. When the villi are destroyed, nutrient absorption is hindered, which can lead to serious health complications.

How serious? The autoimmune reaction of celiac (basically, the immune systems mistakes parts of the body as a foreign invader, and attacks the body’s own tissues) can lead to other autoimmune conditions like rheumatoid arthritis or thyroid dysfunction.

A recent study has determined that the incidence of celiac disease has doubled every year since 1974, and it also increases with age. If people can develop celiac disease in their 50s and 60s, it indicates that the condition is likely caused by environmental factors.

One important possible environmental trigger of the disease that may be causing late-onset celiac is changes in the composition of gut bacteria. Researchers suggested that a greater understanding of these changes in the gut may allow for the development of a way to keep the disease on hold.

Our gut health is truly related to the health of the rest of the body. Start by healing your gut, and maintaining that health to build a strong foundation that the rest of the body can benefit from, well into our golden years.

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“It is possible for a person to be too clean for their own good.” This is a recent quote from Allison Aiello, visiting associate professor of epidemiology at Harvard, who is studying the effect of frequent handwashing with antimicrobial soap containing triclosan, or 2,4,4’-trichloro-2’-hydroxydiphenyl ether. Her research has shown an increase in allergies and hay fever in children and teens with chronic use of soap products containing triclosan.

Handwashing with a powerful soap containing triclosan brings up two questions:

1. What is the effect of chronic removal of hand bacteria? We know where these hands go, especially in children (the mouth, for starters).

2. What could this chemical be doing to our body from a metabolic/hormonal perspective?

My input:
1. Science has now discovered that people normally have over a 1000 different species of bacteria not only in our intestinal tract, but also on our skin. This fact points out the normal symbiotic balance with microbes that we have evolved with for millions of years. The human/microbe symbiosis is especially important in childhood immune development. Research and clinical observations support the “Hygiene Theory,” which states that a lack of early childhood exposure to infectious and symbiotic microorganisms and parasites increases susceptibility to allergic diseases (like allergies, asthma, dermatitis, and autoimmune diabetes) by disrupting the natural development of the immune system. Children living in non-industrial countries and closer to nature generally don’t have these problems.

2. Triclosan is also used in toothbrushes, ice-making machines, and in pesticides! This type of exposure has led to research by concerned individuals who have now shown significant evidence that it is yet another toxin with hormone-disrupting qualities which could majorly affect immunity. Due to the increase in negative evidence, the FDA has decided to thoroughly investigate triclosan, but not until 2013—a decade earlier than previously planned!

So what are the solutions? First, take a high quality probiotic and also make your own cultured foods. We may soon find topical probiotics could be beneficial, as well. Second, find safe soaps and use them mostly after exposure to public places. Safe soaps (or hand sanitizers) can be found at www.ewg.org, under cleansing products – hand sanitizers. Third, get involved in social networking by joining “green”groups to help educate and promote the changes we desperately need.

http://www.epa.gov/oppsrrd1/REDs/factsheets/triclosan_fs.htm

Leonard Smith, M.D.Dr. Leonard Smith is a prominent Board-Certified, general, gastrointestinal and vascular surgeon who had a successful private practice for 25 years. In addition to his active surgery practice, he also incorporated lifestyle, diet, supplementation, exercise, detoxification, and stress management into many of the therapies he would prescribe. Many of his patients with cancer, cardiovascular disease, and other serious illnesses did so well under his treatment regimes that he began to devote most of his career to foundational health care and preventive medicine.

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Doing what I do, I have a lot of folks come to me with problems like heartburn, constipation, gas and bloating—things that make you think right off the bat, “That’s a digestive issue.” But what about problems like fatigue or weight gain? Even allergies, joint pain or skin problems? What a lot of people don’t realize is that all of these things are connected, and they all come back to your gut.

I have a new book coming out called The Road to Perfect Health, and in it I talk about the vast numbers of bacteria in your body, especially in your digestive tract (which is where roughly 80 percent of your natural defenses are found). And when a healthy digestive balance is upset because of things like poor diet, stress or other factors, the result can be not only poor digestion, but a total breakdown in health.

If you’ve been having persistent health problems that you and your doctor just can’t seem to figure out no matter what you try, it may be time to look at what’s going on in your gut. And to do that, there are two absolutely essential tests that I recommend starting with. One is called a comprehensive stool analysis (CDSA or CSAP) and it’s really pretty remarkable. It evaluates your poop (now don’t cringe, this is important!) and looks at things like how you are digesting your food, as well as your levels of good and bad bacteria, whether pathogenic organisms such as C. difficile are present, what your yeast levels are, and if there are parasites in the gut.

The CDSA will also show you whether you have Leaky Gut Syndrome or inflammation in your digestive system, and it will show you how well your gut immunity is working, along with important gut health markers such as pH, blood, short-chain fatty acids and even how well your pancreas is functioning. These are all extremely important aspects of gut health that together can help you get to the bottom of what is going on in the rest of your body. Again, I can’t stress enough how connected your overall health is to what’s going on in your gut!

The other test is a gluten sensitivity test. Why gluten sensitivity? Because wheat gluten is a major (if not the worst) food irritant to the digestive system, and it is in a huge number of products on the market today—not just bread. Seriously folks, more than 40 percent of Americans are gluten sensitive and most don’t even know it, and 2 million of those have a serious autoimmune disorder called celiac disease, which causes the body to try to attack gluten in the system. And because even a lot of GI doctors don’t understand the difference between gluten sensitivity and celiac disease, most will either label you as having celiac or nothing, which can be extremely frustrating when you don’t feel well and are trying to figure out what’s wrong (read more about this here).The bottom line is that people are having all these problems which could lead to bigger problems later on, and the reality is those problems can be helped.

Both of these tests are non-invasive and can be done right at home (visit www.labtestingdirect.com and www.enterolab.com for more information). Then, all you have to do is send the tests to the lab for analysis (prepaid envelopes are provided) and hopefully take the first step toward getting your health back on track. If they seem expensive, think about it this way: how much money do you spend each week or each month on frivolous things you really don’t need? Isn’t your health a hundred times more important than a $4 latte every morning? And even if your insurance doesn’t cover the cost right away, you may be eligible for reimbursement, so I beg you—make this investment in your health. It’s worth it to get to the root of your problems and start enjoying the vibrant health and energy you deserve!!

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Here’s something I thought you might find interesting: researchers at Harvard University Medical School recently discovered that bacteria in the gut can trigger the autoimmune response associated with rheumatoid arthritis.

In simple terms, an autoimmune response means that there’s an immune response in the body that goes astray, causing the body to attack its own tissues instead of a foreign invader, in this case causing the breakdown in healthy joint cartilage seen in people with rheumatoid arthritis.

So what does all this mean when it comes to the trillions of bacteria living in your digestive tract every day? It means that they can affect your whole body, sometimes even causing conditions nowhere near the gut, and it’s something I’ve been saying for years! Not only that, but more and more studies these days are proving me right, showing that many autoimmune conditions begin right in the gut.

This isn’t surprising, since more than 70% of your body’s immune defenses are found in the gut—and when things like digestive problems, gut bacteria imbalance and toxin overload put a strain on the immune system, it often leads to the development of autoimmune conditions. 

The folks at Harvard are planning to look at the effects of intestinal bacteria on other autoimmune conditions as well, including type 1 diabetes, so stay tuned! And remember to take good care of your gut!

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